About LAM

Lymphangioleiomyomatosis (LAM) is a rare, multi-system disease that was first described in the medical literature by von Stossel in 1937. The disease involves the lungs, kidneys and lymphatics, and is characterized by an unusual type of abnormal smooth muscle cell that destroys normal lung tissue, obstructs small airways and lymphatics, and reduces oxygen intake by the lungs, often leading to respiratory failure.  Recent thinking about LAM suggests that it may in fact be a form of cancer.

Lymphangioleiomyomatosis is pronounced lim - fan'- je - o - Li'- o - mi'- o - ma - to'- sis. "Lymph" and "angio" refer to the lymph and blood vessels. "Leiomyomatosis" refers to the formation of the bundles of the unusual muscle cells.


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